Concepedia

6-Mercaptopurine, an activator of Nur77, enhances transcriptional activity of HIF-1α resulting in new vessel formation

Y H Yoo, T-Y Na, W-K Yang, I-K Lee, Gu Kong, J-H Chung, M-O Lee

Oncogene · 2006 · 48 citations · 52 references

DOI

Concepts

References

52

Regulation of hypoxia-inducible factor 1α is mediated by an O <sub>2</sub> -dependent degradation domain via the ubiquitin-proteasome pathway

Eric Huang, Jie Gu, Maureen Schau et al. · Proceedings of the National Academy of Sciences · 1998 · 2.1K citations · Full text

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Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions

Susana Alicia Salceda, J. Jaime · Journal of Biological Chemistry · 1997 · 1.7K citations · Full text

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

David Lando, Daniel J. Peet, Jeffrey J. Gorman et al. · Genes & Development · 2002 · 1.5K citations · Full text

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Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

Takashi Chijiwa, Akihiko Mishima, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 1.5K citations · Full text

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FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

Patrick C. Mahon, Kiichi Hirota, Gregg L. Semenza · Genes & Development · 2001 · 1.4K citations · Full text

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