Masatoshi Hagiwara

Phosphorylated CREB binds specifically to the nuclear protein CBP

John C. Chrivia, Roland P.S. Kwok, Ned Lamb et al. · Nature · 1993 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +5

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

Takashi Chijiwa, Akihiko Mishima, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 1.5K citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA

Daisuke Kaida, Hajime Motoyoshi, Etsu Tashiro et al. · Nature Chemical Biology · 2007 · 655 citations

Life Sciences, Genetics, Molecular Biology +13

KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II.

Hiroshi Tokumitsu, Takashi Chijiwa, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 625 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

The newly synthesized selective Ca2+calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

Mariko Sumi, Kazutoshi Kiuchi, Tomohiko Ishikawa et al. · Biochemical and Biophysical Research Communications · 1991 · 509 citations

Life Sciences, Neuroscience, Pharmacology +14