Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

Déborah Tribouillard‐Tanvier, Suzana Dos Reis, Fabienne Gug, Cécile Voisset, Vincent Béringue, Raimon Sabaté, Ema Kikovska, Nicolas Talarek, Stéphane Bach, Chenhui Huang,

PLoS ONE · 2008 · 63 citations · 48 references

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Abstract

6AP and GA are therefore the first compounds to selectively inhibit the protein folding activity of the ribosome. They thus constitute precious tools to study the yet largely unexplored biological role of this protein folding activity.

References

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