Hepatitis C virus core protein epigenetically silences SFRP1 and enhances HCC aggressiveness by inducing epithelial–mesenchymal transition

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

Takaji Wakita, Thomas Pietschmann, Takanobu Kato et al. · Nature Medicine · 2005 · 2.7K citations · Full text

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Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

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Life Sciences, Genetics, Molecular Biology +17

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

Hiromu Suzuki, D. Neil Watkins, Kam-Wing Jair et al. · Nature Genetics · 2004 · 1.1K citations

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Michael R. Rountree, Kurtis E. Bachman, Stephen B. Baylin · Nature Genetics · 2000 · 1K citations

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

François Fuks, Wendy A. Burgers, Alexander Brehm et al. · Nature Genetics · 2000 · 973 citations

Life Sciences, Genetics, Molecular Biology +12