Annals of Surgery · 2008 · 101 citations · 32 references
Our study failed to demonstrate any clear advantage of routine postoperative immunonutrition in patients undergoing elective upper gastrointestinal surgery. Both enteral and parenteral treatment options showed similar efficacy, tolerance, and effects on protein synthesis. Parenteral nutrition composed according to contemporary rules showed similar efficiency to enteral nutrition. However, because of its cost-efficiency, enteral therapy should be considered as the treatment of choice in all patients requiring nutritional therapy.
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Perioperative Total Parenteral Nutrition in Surgical Patients
New England Journal of Medicine · 1991 · 1.2K citations · Full text