Concepedia

p53-induced protein with a death domain (PIDD) isoforms differentially activate nuclear factor-kappaB and caspase-2 in response to genotoxic stress

Solange Cuenin, Antoine Tinel, Sophie Janssens, J Tschopp

Oncogene · 2007 · 59 citations · 17 references

DOI

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17

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

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Requirement for Caspase-2 in Stress-Induced Apoptosis Before Mitochondrial Permeabilization

Patrice Lassus, Ximena Opitz-Araya, Yuri Lazebnik · Science · 2002 · 717 citations

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The PIDDosome, a Protein Complex Implicated in Activation of Caspase-2 in Response to Genotoxic Stress

Antoine Tinel, Jürg Tschopp · Science · 2004 · 666 citations

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Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress

Tony T. Huang, Shelly M. Wuerzberger‐Davis, Zhao‐Hui Wu et al. · Cell · 2003 · 552 citations · Full text

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Caspase-2 Induces Apoptosis by Releasing Proapoptotic Proteins from Mitochondria

Yin Guo, Srinivasa M. Srinivasula, Anne Druilhe et al. · Journal of Biological Chemistry · 2002 · 517 citations · Full text

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