Spray freezing into liquid versus spray-freeze drying: Influence of atomization on protein aggregation and biological activity

Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

C. C. F. Blake, D. F. Koenig, G. A. Mair et al. · Nature · 1965 · 1.7K citations

Life Sciences, Biochemistry, Biophysics +11

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

Jeffrey L. Cleland, Melissa Powell, S J Shire · PubMed · 1993 · 542 citations

Pharmacy, Biochemistry, Pharmaceutics +17

Protein Inhalation Powders: Spray Drying vs Spray Freeze Drying

Yuh‐Fun Maa, Phuong‐Anh Nguyen, Theresa D. Sweeney et al. · Pharmaceutical Research · 1999 · 354 citations

Pharmacy, Food Science, Pharmaceutics +10

Protein denaturation by combined effect of shear and air-liquid interface

Yuh‐Fun Maa, Chung C. Hsu · Biotechnology and Bioengineering · 1997 · 349 citations · Full text

Natural Sciences, Biochemistry, Biophysics +15

Separation of Freezing- and Drying-Induced Denaturation of Lyophilized Proteins Using Stress-Specific Stabilization

John F. Carpenter, Steven J. Prestrelski, Tsutomu Arakawa · Archives of Biochemistry and Biophysics · 1993 · 330 citations

Life Sciences, Biochemistry, Food Science +14