Concepedia

4217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy

Kazuyuki Inoue, Eri Suzuki, Toshiki Takahashi, Yoshiaki Yamamoto, Rei Yazawa, Yukitoshi Takahashi, Katsumi Imai, Kou Miyakawa, Yushi Inoue, Daiki Tsuji,

Epilepsy Research · 2014 · 11 citations · 16 references

DOI

Concepts

References

16

Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses

Franz Faul, Edgar Erdfelder, Axel Buchner et al. · Behavior Research Methods · 2009 · 36K citations · Full text

, , +11

Effect of Aging on Glucuronidation of Valproic Acid in Human Liver Microsomes and the Role of UDP-Glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10

Upendra A. Argikar, Rory P. Remmel · Drug Metabolism and Disposition · 2008 · 131 citations · Full text

, , +14

Asymptomatic Hyperammonemia in Patients Receiving Valproic Acid

J. V. Murphy · Archives of Neurology · 1982 · 129 citations

, , +13

New insights on the mechanisms of valproate-induced hyperammonemia: Inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA

C. C. P. Aires, Arno van Cruchten, Lodewijk IJlst et al. · Journal of Hepatology · 2010 · 115 citations

, , +10

Cloning and expression of the human N-acetylglutamate synthase gene

Ljubica Caldovic, Hiroki Morizono, Maria Panglao et al. · Biochemical and Biophysical Research Communications · 2002 · 85 citations

, , +6