Concepedia

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: Studies with halofantrine

Christopher J. H. Porter, Ann Marie Kaukonen, Agnes Taillardat‐Bertschinger, Ben J. Boyd, Jacquelyn M. O'Connor, Glenn A. Edwards, William N. Charman

Journal of Pharmaceutical Sciences · 2004 · 217 citations · 29 references

DOI

Concepts

References

29

Lipid-based vehicles for the oral delivery of poorly water soluble drugs

Andrew Humberstone, William N. Charman · Advanced Drug Delivery Reviews · 1997 · 579 citations

, , +16

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings

Olle Hernell, Joan E. Staggers, Martin C. Carey · Biochemistry · 1990 · 484 citations

, , +15

Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products

Leab Sek, Christopher J. H. Porter, Ann Marie Kaukonen et al. · Journal of Pharmacy and Pharmacology · 2002 · 303 citations

, , +17

Effect of Short‐, Medium‐, and Long‐Chain Fatty Acid‐Based Vehicles on the Absolute Oral Bioavailability and Intestinal Lymphatic Transport of Halofantrine and Assessment of Mass Balance in Lymph‐Cannulated and Non‐cannulated Rats

Suzanne M. Caliph, William N. Charman, Christopher J. H. Porter · Journal of Pharmaceutical Sciences · 2000 · 293 citations

, , +16

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings

Joan E. Staggers, Olle Hernell, Richard J. Stafford et al. · Biochemistry · 1990 · 286 citations

, , +17