A novel retinoic/butyric hyaluronan ester for the treatment of acute promyelocytic leukemia: preliminary preclinical results

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

Hugues de Thé, Catherine Lavau, Agnès Marchio et al. · Cell · 1991 · 1.4K citations

Life Sciences, Molecular Biology, Molecular Genetics +10

4‐Dialkylaminopyridines as Highly Active Acylation Catalysts. [New synthetic method (25)]

Gerhard Höfle, Wölfgang Steglich, Helmut Vorbrüggen · Angewandte Chemie International Edition in English · 1978 · 1.2K citations

Natural Sciences, Chemistry, Carbohydrate Chemistry +16

PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL SYSTEMS

Ruth I. Geran, Nathaniel H. Greenberg, Marylea MacDonald et al. · Cancer chemotherapy reports. Part 1 · 1972 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +8

Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia

Ari Melnick, Jonathan D. Licht · Blood · 1999 · 1K citations

Medicine, Molecular Biology, Oncology +12

Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia

F Grignani, Silvia De Matteis, Clara Nervi et al. · Nature · 1998 · 1K citations

Life Sciences, Cancer Biology, Molecular Biology +14