In Vitro and in Vivo Evaluation of Ruthenium(II)−Arene PTA Complexes

C. Scolaro, Alberta Bergamo, L. Brescacin, +6

Journal of Medicinal Chemistry

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

Alberta Bergamo, Gianni Sava

Dalton Transactions

Pharmaceutical ScienceChemoprevention StrategyRuthenium Anticancer CompoundsChemistryPharmaceutical Chemistry +18

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

Suzanne Leijen, Sjaak A. Burgers, Paul Baas, +7

Investigational New Drugs

OncologyPhase I/ii StudyMedicineBronchial NeoplasmPharmacotherapy +8

Organometallic ruthenium-based antitumor compounds with novel modes of action

Wee Han Ang, Angela Casini, Gianni Sava, +1

Journal of Organometallic Chemistry

Medicinal ChemistryNovel ModesNatural SciencesAnti-cancer AgentChemistry +2

Cis- and trans-dihalotetrakis(dimethyl sulfoxide)ruthenium(II) complexes (RuX2(DMSO)4; X = Cl, Br): synthesis, structure, and antitumor activity

Enzo Alessio, G. Mestroni, G. Nardin, +4

Inorganic Chemistry

Inorganic ChemistryMedicinal ChemistryDimethyl SulfoxideAntitumor ActivityBiochemistry +10

Metal-based antitumour drugs in the post-genomic era: what comes next?

Gianni Sava, Alberta Bergamo, Paul J. Dyson

Dalton Transactions

Drug TargetMolecular Biology'Metal-based Antitumour DrugsDalton Trans.Drug Resistance +15

Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.

Gianni Sava, Sonia Zorzet, Francesca Vita, +8

PubMed

Lung MetastasesPathologySelective TargetingCancer BiologyTumor Biology +15

Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A

Gianni Sava, Alberta Bergamo, Sonia Zorzet, +9

European Journal of Cancer

Inorganic ChemistryChemical StabilityChemistryHeterocycle ChemistryPharmacology +3

Modulation of the metastatic progression of breast cancer with an organometallic ruthenium compound.

Alberta Bergamo, Alessia De Masi, Paul J. Dyson, +1

PubMed

Breast OncologyCollagen IvCancer BiologyTumor BiologyOncology +17

Development of Ruthenium Antitumor Drugs that Overcome Multidrug Resistance Mechanisms

Carsten A. Vock, Wee Han Ang, C. Scolaro, +6

Journal of Medicinal Chemistry