Hugues de Thé

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

Hugues de Thé, Catherine Lavau, Agnès Marchio et al. · Cell · 1991 · 1.4K citations

Hematological Malignancy, Transcriptional Regulation, Pml-rarα Fusion Mrna +8

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

Hugues de Thé, Christine Chomienne, Michel Lanotte et al. · Nature · 1990 · 1.4K citations

Hematological Malignancy, Acute Promyelocytic Leukaemia, Mixed-phenotype Acute Leukemia +8

Identification of a second human retinoic acid receptor

Nigel J. Brand, Martin Petkovich, Andrée Krust et al. · Nature · 1988 · 1K citations

Photoreceptor Cell, Retina, Signal Transduction +3

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

Hugues de Thé, María dM Vivanco, Pierre Tiollais et al. · Nature · 1990 · 1K citations

Signal Transduction, Molecular Physiology, Retinoic Acid Receptor +9

Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML

Xiaowei Zhang, Xiaojing Yan, Zi‐Ren Zhou et al. · Science · 2010 · 765 citations

Apoptosis, Arsenic Trioxide Controls, Molecular Biology +18