Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics · 2003 · 2K citations

Life Sciences, Cell Biology, Physiology +14

Polycystin-2 is an intracellular calcium release channel

Peter Koulen, Yiqiang Cai, Lin Geng et al. · Nature Cell Biology · 2002 · 714 citations

Life Sciences, Biochemistry, Cell Biology +12

Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist

Vincent H. Gattone, Xiaofang Wang, Peter C. Harris et al. · Nature Medicine · 2003 · 669 citations

Medicine, Nephrology, Pharmacology +8

Somatic Inactivation of Pkd2 Results in Polycystic Kidney Disease

Guanqing Wu, Vivette D. D’Agati, Yiqiang Cai et al. · Cell · 1998 · 572 citations · Full text

Medicine, Genetics, Molecular Genetics +15

cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway

Tamio Yamaguchi, Jill C. Pelling, Nadja T. Ramaswamy et al. · Kidney International · 2000 · 353 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15