Concepedia

Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells

Wen‐Chun Hung, Wei‐Lung Tseng, Jentaie Shiea, Hui‐Chiu Chang

Cancer Letters · 2009 · 109 citations · 26 references

DOI

Concepts

References

26

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Gabriele Bergers, Rolf A. Brekken, Gerald McMahon et al. · Nature Cell Biology · 2000 · 2.8K citations · Full text

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Andrea C. Carrano, Esther Eytan, Avram Hershko et al. · Nature Cell Biology · 1999 · 1.5K citations

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Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

Peggy L. Porter, Kathleen E. Malone, Patrick J. Heagerty et al. · Nature Medicine · 1997 · 918 citations

, , +14

Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication

Kei Nakayama · The EMBO Journal · 2000 · 710 citations · Full text

, , +16

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

Hedwig Sutterlüty, Eric Chatelain, Alain Marti et al. · Nature Cell Biology · 1999 · 699 citations

, , +12