Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies

Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer

Jan B. Vermorken, Fernando Rivera, Éva Remenár et al. · New England Journal of Medicine · 2008 · 3.7K citations · Full text

Medicine, Oncology, Pharmacology +16

Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20

ME Reff, K Carner, KS Chambers et al. · Blood · 1994 · 1.9K citations · Full text

Life Sciences, Immunology, Pathology +14

Humanization of an anti-p185HER2 antibody for human cancer therapy.

Paul Carter, Leonard G. Presta, C Gorman et al. · Proceedings of the National Academy of Sciences · 1992 · 1.9K citations

Pharmacy, Molecular Biology, Oncology +16

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

K. T. Brunner, Jacques Mauël, J C Cerottini et al. · PubMed · 1968 · 1.4K citations · Full text

Life Sciences, Cell Biology, Immunology +10

An enzyme-release assay for natural cytotoxicity

Carol Korzeniewski, Denis M. Callewaert · Journal of Immunological Methods · 1983 · 1.1K citations

Life Sciences, Biochemistry, Toxicology +12