In vitro antidiabetic activity of psidium guajava leaves extracts

Abstract

To evaluate the glucose uptake of (antidiabetic activity) crude n-hexane, ethanol, ethanol and aqueous leaf extracts of P. guajava. P. guajava leaf extracts were subjected to inhibitory effect of glucose utilization using specific standard in vitro procedure. Results in four different leaf extracts revealed that, the methanol extract at a concentration of 50g plant extract/l was found to be more potent than other extracts with the lowest mean glucose concentration of 201+1.69 mg/dl at the end of 27 hrs. The present findings suggest that, the methanolic extract showed a significant inhibitory effect on glucose diffusion in vitro thus validating the traditional claim of the plant.