PERITRANSPLANT TOLERANCE INDUCTION IN MACAQUES: EARLY EVENTS REFLECTING THE UNIQUE SYNERGY BETWEEN IMMUNOTOXIN AND DEOXYSPERGUALIN1,2

Abstract

The study suggests DSG arrests DC maturation. The unusual synergy of immunotoxin and DSG apparently involves coincidental reduction in lymph node T cell mass and mature DC, a transient circumstance favoring development of stable tolerance.