Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

Tomasz Szkudelski · Physiological Research · 2001 · 2.8K citations · Full text

Rat Pancreas, Lipid Peroxidation, Cell Death +19

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

Fabrizio Thorel, Virginie Népote, Isabelle Avril et al. · Nature · 2010 · 1.1K citations · Full text

Developmental Biology, Pancreatic Cancer, Medicine +7

Studies of pancreatic alpha cell function in normal and diabetic subjects

Roger H. Unger, E Aguilar-Parada, Walter A. Müller et al. · Journal of Clinical Investigation · 1970 · 834 citations · Full text

Pancreas Transplantation, Insulin Signaling, Metabolic Syndrome +17

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients

Hiroyasu Sakuraba, Hiroki Mizukami, Nobuo Yagihashi et al. · Diabetologia · 2002 · 678 citations · Full text

Metabolic Syndrome, Biochemistry, Natural Sciences +9