Yumi Takiyama

Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

Yumi Takiyama, Tatsuo Harumi, Jun Watanabe et al. · Diabetes · 2011 · 164 citations · Full text

Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy

Ryoichi Bessho, Yumi Takiyama, Takao Takiyama et al. · Scientific Reports · 2019 · 156 citations · Full text

High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein

Tsubasa Isoe, Yuichi Makino, Katsutoshi Mizumoto et al. · Kidney International · 2010 · 148 citations · Full text

Metabolic Syndrome, Insulin Signaling, Signal Transduction +10

Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice

Yasutaka Takeda, Yukihiro Fujita, Jun Honjo et al. · Diabetologia · 2011 · 119 citations · Full text

Insulin Signaling, Biochemistry, Medicine +9

Upregulated IL-18 expression in type 2 diabetic subjects with nephropathy: TGF-β1 enhanced IL-18 expression in human renal proximal tubular epithelial cells

Kazunari Miyauchi, Yumi Takiyama, Jun Honjyo et al. · Diabetes Research and Clinical Practice · 2008 · 88 citations

Renal Pathology, Immunology, Renal Inflammation +17