Concepedia

Publication | Open Access

Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

DOIFull Paper Access

164

Citations

40

References

2011

Year

Yumi Takiyama, Tatsuo Harumi, Jun Watanabe, Yukihiro Fujita, Jun Honjo, Norihiko Shimizu, Yuichi Makino, Masakazu Haneda
Diabetes

Abstract

Our data suggest that hypoxia-induced HIF-1α accumulation in diabetic nephropathy could be suppressed by the antidiabetes drug, metformin, through the repression of oxygen consumption.

References

YearCitations

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