Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety - Concepedia

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Publication | Open Access

Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety

DOI Full Paper Access

197

Citations

40

References

2010

Year

Youssef Daali, Michel Wagner, Gérard Hopfgartner, M. Rebsamen, MF Rossier, D Hochstrasser, Pierre Dayer, JA Desmeules

British Journal of Pharmacology

Abstract

The modulation of CYP2D6 and CYP3A activities had clear effects on oxycodone pharmacodynamics and these effects were dependent on CYP2D6 genetic polymorphism.

References

	Year	Citations

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