Evan D. Kharasch

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites

Bojan Lalovic, Evan D. Kharasch, Danny D. Shen · Clinical Pharmacology & Therapeutics · 2006 · 416 citations

Medicine, Pharmacokinetics, Pharmacology +10

Clinical Pharmacogenetics Implementation Consortium Guideline for <i>CYP2D6</i>, <i>OPRM1</i>, and <i>COMT</i> Genotypes and Select Opioid Therapy

Kristine R. Crews, Andrew A. Monte, Rachel Huddart et al. · Clinical Pharmacology & Therapeutics · 2021 · 399 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Psychedelic Effects of Ketamine in Healthy Volunteers 

Andrew T. Bowdle, Allen D. Radant, Deborah S. Cowley et al. · Anesthesiology · 1998 · 371 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

Kristine R. Crews, Andrea Gaedigk, Henry M. Dunnenberger et al. · Clinical Pharmacology & Therapeutics · 2011 · 368 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Transcriptional Control of Intestinal Cytochrome P-4503A by 1α,25-Dihydroxy Vitamin D3

Kenneth E. Thummel, Cynthia Brimer, Kazuto Yasuda et al. · Molecular Pharmacology · 2001 · 324 citations

Life Sciences, Biochemistry, Pharmacology +17