BSE and vCJD cause disturbance to uric acid levels

Normal host prion protein necessary for scrapie-induced neurotoxicity

Sebastian Brandner, Stefan Isenmann, Alex J. Raeber et al. · Nature · 1996 · 810 citations

Veterinary Medicine, Infectious Diseases, Neuroscience +14

Depleting Neuronal PrP in Prion Infection Prevents Disease and Reverses Spongiosis

Giovanna R. Mallucci, Andrew Dickinson, Jacqueline M. Linehan et al. · Science · 2003 · 760 citations

Life Sciences, Neurobiology, Neuroscience +17

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

David Peretz, R. Anthony Williamson, Kiotoshi Kaneko et al. · Nature · 2001 · 524 citations

Veterinary Medicine, Cell Biology, Molecular Biology +11

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

David R. Brown, Bernhard Schmidt, Hans A. Kretzschmar · Nature · 1996 · 503 citations

Life Sciences, Neurobiology, Neuroscience +14

Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt–Jakob disease

Inga Zerr, Maurizio Pocchiari, Steven Collins et al. · Neurology · 2000 · 479 citations

Life Sciences, Biology, Evolutionary Biology +15