Concepedia

Normal host prion protein necessary for scrapie-induced neurotoxicity

Sebastian Brandner, Stefan Isenmann, Alex J. Raeber, Marek Fischer, Andreas W. Sailer, Yasushi Kobayashi, Silvia Marino, Charles Weissmann, Adriano Aguzzi

Nature · 1996 · 810 citations · 19 references

DOI

Concepts

References

19

A simple method of estimating 50 per cent end points

Hr Muench · Medical Entomology and Zoology · 1938 · 8.4K citations

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Mice devoid of PrP are resistant to scrapie

Hansruedi Büeler, Adriano Aguzzi, Andreas W. Sailer et al. · Cell · 1993 · 2.1K citations · Full text

, , +8

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

Hansruedi Büeler, Marek Fischer, Yolande Lang et al. · Nature · 1992 · 1.7K citations · Full text

, , +13

A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

Nicole Schaeren‐Wiemers, A. Gerfin-Moser · Histochemistry and Cell Biology · 1993 · 1.2K citations

, , +14

Neurotoxicity of a prion protein fragment

Gianluigi Forloni, Nadia Angeretti, Roberto Chiesa et al. · Nature · 1993 · 943 citations

, , +12