Discovery of novel isoxazolines as anti-tuberculosis agents

A Simple Catalytic Method for the Conversion of Aryl Bromides to Arylamines

Anil S. Guram, Roger A. Rennels, Stephen L. Buchwald · Angewandte Chemie International Edition in English · 1995 · 1K citations

Facile Pd-catalyzed Method, Chemical Engineering, Cross-coupling Reaction +13

Comparison of a Miniaturized Shake-Flask Solubility Method with Automated Potentiometric Acid/Base Titrations and Calculated Solubilities

Alexander Glomme, Joachim März, Jennifer Dressman · Journal of Pharmaceutical Sciences · 2004 · 290 citations

Calculated Solubilities, Medicine, Analytical Chemistry +6

Combinatorial Lead Optimization of [1,2]-Diamines Based on Ethambutol as Potential Antituberculosis Preclinical Candidates

Richard Lee, Marina Protopopova, Emma T. Crooks et al. · Journal of Combinatorial Chemistry · 2003 · 208 citations

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +15

Inhibition of the Antibacterial Target UDP-(3-<i>O</i>-acyl)-<i>N</i>-acetylglucosamine Deacetylase (LpxC):  Isoxazoline Zinc Amidase Inhibitors Bearing Diverse Metal Binding Groups

Michael C. Pirrung, L. Nathan Tumey, Christian R.H. Raetz et al. · Journal of Medicinal Chemistry · 2002 · 106 citations · Full text

Bioorganic Chemistry, Zinc Amidase, Gram Negative Bacteria +16

Synthesis and Evaluation of Cyclic Secondary Amine Substituted Phenyl and Benzyl Nitrofuranyl Amides as Novel Antituberculosis Agents

Rajendra Tangallapally, Raghunandan Yendapally, Robin E. Lee et al. · Journal of Medicinal Chemistry · 2005 · 98 citations · Full text