Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon, Marie Pancera, Priyamvada Acharya, +50

Nature Structural & Molecular Biology

Crystal StructureHuman RetrovirusMolecular BiologyConformational StudyStructural Biology +5

Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C

James Μ. Binley, Elizabeth A. Lybarger, Emma T. Crooks, +17

Journal of Virology

Nature of Nonfunctional Envelope Proteins on the Surface of Human Immunodeficiency Virus Type 1

Penny L. Moore, Emma T. Crooks, Lauren L. Porter, +10

Journal of Virology

Viral ReplicationNeutralizing AntibodiesImmunologyMolecular BiologyViral Structural Protein +14

Combinatorial Lead Optimization of [1,2]-Diamines Based on Ethambutol as Potential Antituberculosis Preclinical Candidates

Richard Lee, Marina Protopopova, Emma T. Crooks, +3

Journal of Combinatorial Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryCombinatorial Lead OptimizationBiochemistry +13

Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals

Georgia D. Tomaras, James Μ. Binley, Elin S. Gray, +21

Journal of Virology

Hiv-1-infected IndividualsHumoral ResponseImmunologyCd4 T Cell ResponsesViral Structural Protein +18

An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10

Josh D. Nelson, Florence M. Brunel, Richard Christian Jensen, +9

Journal of Virology

ImmunologyMolecular BiologyViral Structural ProteinVirus StructureHuman Retrovirus +15

Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization

James Μ. Binley, Yih‐En Andrew Ban, Emma T. Crooks, +4

Journal of Virology

GlycobiologyImmunologyMolecular BiologyViral Structural ProteinImmunotherapy +15

A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120

Emma T. Crooks, Penny L. Moore, Michael Franti, +11

Virology

Viral ReplicationHuman RetrovirusHiv-1 Virus-like ParticlesImmunologyAntiviral Response +6

Improved Induction of Antibodies against Key Neutralizing Epitopes by Human Immunodeficiency Virus Type 1 gp120 DNA Prime-Protein Boost Vaccination Compared to gp120 Protein-Only Vaccination

Michael Vaine, Shixia Wang, Emma T. Crooks, +4

Journal of Virology

VaccinationAllergyVaccine DevelopmentKey Neutralizing EpitopesNeurovirology +13

Antibody Responses Elicited in Macaques Immunized with Human Immunodeficiency Virus Type 1 (HIV-1) SF162-Derived gp140 Envelope Immunogens: Comparison with Those Elicited during Homologous Simian/Human Immunodeficiency Virus SHIV_SF162P4and Heterologous HIV-1 Infection

Nina Derby, Zane Kraft, Elaine Kan, +5

Journal of Virology

ImmunodeficienciesImmunologyImmunodominanceImmunotherapeuticsAntiviral Drug +17