Targeted sequence alteration of a chromosomal locus in mouse liver

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

F Liu, Young Song, D Liu · Gene Therapy · 1999 · 1.7K citations

Xenotransplantation, Engineering, Molecular Biology +10

High Levels of Foreign Gene Expression in Hepatocytes after Tail Vein Injections of Naked Plasmid DNA

G Zhang, Vladimir G. Budker, Jon A. Wolff · Human Gene Therapy · 1999 · 947 citations

Biomedical Research, Genetics, Molecular Biology +24

Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes

Akinori Egashira, K. Yamauchi, Kaoru Yoshiyama et al. · DNA repair · 2002 · 85 citations

Knockout Mouse, Genome Instability, Developmental Biology +7

A novel positive detection system of in vivo mutations in rpsL (strA) transgenic mice

Yoichi Gondo, Yoshiyuki Shioyama, Kazuki Nakao et al. · Mutation Research/Environmental Mutagenesis and Related Subjects · 1996 · 65 citations

Knockout Mouse, Signal Transduction, Engineering +13

Transient activation of transgene expression by hydrodynamics-based injection may cause rapid decrease in plasmid DNA expression

Hiroshi Ochiai, Masahiro Fujimuro, H. Yokosawa et al. · Gene Therapy · 2007 · 41 citations

Plasmid Dna Expression, Transient Activation, Transgene Expression +11