Concepedia

Identification of Differential Responses to an Oral Glucose Tolerance Test in Healthy Adults

Ciara Morris, Colm M. O’Grada, Miriam Ryan, Helen M. Roche, Michael J. Gibney, Eileen R. Gibney, Lorraine Brennan

PLoS ONE · 2013 · 90 citations · 30 references

DOIFull text

Open access

Abstract

This work demonstrated that there were four distinct metabolic responses to the OGTT. Classification of subjects based on their response curves revealed an "at risk" metabolic phenotype.

References

30

<b>mixtools</b>: An<i>R</i>Package for Analyzing Finite Mixture Models

Tatiana Benaglia, Didier Chauveau, David R. Hunter et al. · Journal of Statistical Software · 2009 · 1.3K citations · Full text

, , +15

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.

Ying Lee, Hitoshi Hirose, Makoto Ohneda et al. · Proceedings of the National Academy of Sciences · 1994 · 824 citations · Full text

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

T. Andrew Clayton, David Baker, John C. Lindon et al. · Proceedings of the National Academy of Sciences · 2009 · 756 citations · Full text

, , +21

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.

Yun Zhou, V. Grill · Journal of Clinical Investigation · 1994 · 686 citations · Full text

Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels

Kristina M. Utzschneider, Ronald L. Prigeon, Mirjam Faulenbach et al. · Diabetes Care · 2008 · 562 citations · Full text