Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.

Ying Lee, Hitoshi Hirose, Makoto Ohneda, +3

Proceedings of the National Academy of Sciences

Role of nitric oxide in obesity-induced beta cell disease.

Michio Shimabukuro, Makoto Ohneda, Ying Lee, +1

Journal of Clinical Investigation

Nitric OxideInsulin SignalingOxidative StressObesityMetabolic Syndrome +17

Pancreatic β-Cells in Obesity

Joseph L. Milburn, Hiroshi Hirose, Young Ho Lee, +7

Journal of Biological Chemistry

More Direct Evidence for a Malonyl-CoA–Carnitine Palmitoyltransferase I Interaction as a Key Event in Pancreatic β-Cell Signaling

S Chen, Atsushi Ogawa, Makoto Ohneda, +3

Diabetes

Roles of insulin resistance and beta-cell dysfunction in dexamethasone-induced diabetes.

Ai Ogawa, John H. Johnson, Makoto Ohneda, +4

Journal of Clinical Investigation

InflammationMetabolic SyndromeInsulin ResistanceInsulin SignalingDiabetes Management +12

Adrenomedullin in human brain, adrenal glands and tumor tissues of pheochromocytoma, ganglioneuroblastoma and neuroblastoma.

Fumitoshi Satoh, Kazuhiro Takahashi, Osamu Murakami, +7

The Journal of Clinical Endocrinology & Metabolism

High ConcentrationsEndocrine DiseaseTumor TissuesPharmacokineticsNeuro-oncology +19

Immunocytochemical localization of adrenomedullin-like immunoreactivity in the human hypothalamus and the adrenal gland

Fumitoshi Satoh, Kazuhiro Takahashi, Osamu Murakami, +5

Neuroscience Letters

Adrenomedullin-like ImmunoreactivityAdrenal GlandMedicineAdrenal HealthPhysiology +7

Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence

Makoto Ohneda, Lindsey Inman, R. H. Unger

Diabetologia

ObesityMetabolic SyndromeNutritionCaloric RestrictionBody Composition +10

Human brain natriuretic peptide-like immunoreactivity in human brain

Kazuhiro Takahashi, Kazuhito Totsune, Masahiko Sone, +4

Peptides

NeurophysiologyNeuropeptide ReceptorNeuroscienceNeurologyNervous System +3

GLUT2 Expression and Function in β-cells of GK rats with NIDDM: Dissociation Between Reductions in Glucose Transport and Glucose-Stimulated Insulin Secretion

Makoto Ohneda, John H. Johnson, Lindsey Inman, +7

Diabetes