Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (<i><scp>H</scp>umulus lupulus</i>) in vitro and in vivo

Abstract

XH and 8-prenylnaringenin in dietary hops are bioavailable to the target tissues. While hops and XH might be cytoprotective in the liver, 8-prenylnaringenin seems responsible for hop-mediated NQO1 reduction in the mammary gland.