Concepedia

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy

Hong-Min Ni, Benjamin L. Woolbright, Jessica A. Williams, Bryan L. Copple, Wei Cui, James P. Luyendyk, Hartmut Jaeschke, Wen-Xing Ding

Journal of Hepatology · 2014 · 269 citations · 27 references

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References

27

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Taichi Hara, Kenji Nakamura, Makoto Matsui et al. · Nature · 2006 · 3.8K citations

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, Satoshi Waguri, Keiko Taguchi et al. · Nature Cell Biology · 2010 · 2.4K citations

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Impairment of starvation-induced and constitutive autophagy in <i>Atg7</i> -deficient mice

Masaaki Komatsu, Satoshi Waguri, Takashi Ueno et al. · The Journal of Cell Biology · 2005 · 2.3K citations · Full text

, , +15

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

, , +14

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, Jie Yu, Govind Bhagat et al. · Journal of Clinical Investigation · 2003 · 2.2K citations · Full text

, , +15