Treatment of purpura fulminans in meningococcemia with protein C concentrate

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

CT Esmon · Journal of Biological Chemistry · 1989 · 1.1K citations · Full text

Medicine, Biochemistry, Molecular Biology +17

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

Fletcher B. Taylor, Alvin Chang, CT Esmon et al. · Journal of Clinical Investigation · 1987 · 829 citations · Full text

Veterinary Medicine, Biochemistry, Pharmacology +17

Time Course of Hemostatic Abnormalities in Sepsis and its Relation to Outcome

José A. Lorente, Luis J. Garcia‐Frade, Luis Landín et al. · CHEST Journal · 1993 · 314 citations

Veterinary Medicine, Hematology, Infectious Diseases +14

Treatment of Homozygous Protein C Deficiency and Neonatal Purpura Fulminans with a Purified Protein C Concentrate

Marie Dreyfus, Jean François Magny, Françoise Bridey et al. · New England Journal of Medicine · 1991 · 262 citations · Full text

Medicine, Pathology, Pediatrics +17

Mechanism of protein C-dependent clot lysis: role of plasminogen activator inhibitor

Y Sakata, DJ Loskutoff, CL Gladson et al. · Blood · 1986 · 180 citations · Full text

Medicine, Biochemistry, Molecular Biology +14