Concepedia

In vivo antitumor activity and metabolism of a series of 5-deazaacyclotetrahydrofolate (5-DACTHF) analogues

Robert J. Mullin, Barry R. Keith, Eric C. Bigham, David S. Duch, Robert Ferone, Louise S. Heath, Sara C. Singer, Kathleen A. Waters, H.Robert Wilson

Biochemical Pharmacology · 1992 · 11 citations · 23 references

DOI

Concepts

References

23

Chemistry and biology of pteridines 1986

John M. Scott · FEBS Letters · 1987 · 395 citations · Full text

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A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis

G. Peter Beardsley, Barbara A. Moroson, Edward C. Taylor et al. · Journal of Biological Chemistry · 1989 · 230 citations · Full text

, , +14

Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas

T.H. Corbett, Daniel P. Griswold, Bill J. Roberts et al. · Cancer · 1977 · 182 citations

, , +9

Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin

Edward C. Taylor, Peter J. Harrington, Stephen R. Fletcher et al. · Journal of Medicinal Chemistry · 1985 · 148 citations · Full text

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Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase

Samuel Baldwin, Archie Tse, Lynn S. Gossett et al. · Biochemistry · 1991 · 101 citations

, , +8