Eric C. Bigham

Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor

Stephen C. McKeown, David F. Corbett, Aaron S. Goetz et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 69 citations · Full text

Drug Target, Functional Selectivity, Gpr40 Receptor +10

Thallium in organic synthesis. XXXII. Oxidative rearrangement of olefins using thallium(III) nitrate (TTN)

Alexander McKillop, John D. Hunt, Frank Kienzle et al. · Journal of the American Chemical Society · 1973 · 69 citations

Chemical Engineering, Engineering, Heterocyclic +11

2-Acetylpyridine thiocarbonohydrazones. Potent inactivators of herpes simplex virus ribonucleotide reductase

Todd A. Blumenkopf, Joan A. Harrington, Cecilia S. Koble et al. · Journal of Medicinal Chemistry · 1992 · 62 citations

The discovery and optimization of pyrimidinone-containing MCH R1 antagonists

Donald L. Hertzog, Kamal Albarazanji, Eric C. Bigham et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 47 citations · Full text

Medicine, Rational Drug Design, Mechanism Of Action +3

New inhibitors of sepiapterin reductase. Lack of an effect of intracellular tetrahydrobiopterin depletion upon in vitro proliferation of two human cell lines.

Gail K. Smith, David S. Duch, Mark Edelstein et al. · Journal of Biological Chemistry · 1992 · 41 citations · Full text

New Inhibitors, Pharmacotherapy, Sepiapterin Reductase +18