Concepedia

Induction of cyclooxygenase-2 expression by prostaglandin E2 stimulation of the prostanoid EP4 receptor via coupling to Gαi and transactivation of the epidermal growth factor receptor in HCA-7 human colon cancer cells

Kenji Yoshida, Hiromichi Fujino, Sho Otake, Naofumi Seira, John W. Regan, Toshihiko Murayama

European Journal of Pharmacology · 2013 · 28 citations · 26 references

DOI

Concepts

References

26

Prostaglandin E <sub>2</sub> Promotes Colon Cancer Cell Growth Through a G <sub>s</sub> -Axin-ß-Catenin Signaling Axis

Maria Domenica Castellone, Hidemi Teramoto, Bart O. Williams et al. · Science · 2005 · 884 citations

, , +17

Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells

Robert J. Coffey, C J Hawkey, Lars Damstrup et al. · Proceedings of the National Academy of Sciences · 1997 · 316 citations

, , +16

Phosphorylation of Glycogen Synthase Kinase-3 and Stimulation of T-cell Factor Signaling following Activation of EP2 and EP4 Prostanoid Receptors by Prostaglandin E2

Hiromichi Fujino, Kimberly A. West, John W. Regan · Journal of Biological Chemistry · 2002 · 313 citations · Full text

, , +15

Prostaglandin E2 Induced Functional Expression of Early Growth Response Factor-1 by EP4, but Not EP2, Prostanoid Receptors via the Phosphatidylinositol 3-Kinase and Extracellular Signal-regulated Kinases

Hiromichi Fujino, Wei Xu, John W. Regan · Journal of Biological Chemistry · 2003 · 306 citations · Full text

, , +17

Autocrine/Paracrine Prostaglandin E2 Production by Non-small Cell Lung Cancer Cells Regulates Matrix Metalloproteinase-2 and CD44 in Cyclooxygenase-2-dependent Invasion

Mariam Dohadwala, Raj K. Batra, Jie Luo et al. · Journal of Biological Chemistry · 2002 · 260 citations · Full text

, , +14