Toshihiko Murayama

Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes.

Toshihiko Murayama, M Ui · Journal of Biological Chemistry · 1983 · 408 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Studies on the Synthesis and Opioid Agonistic Activities of Mitragynine-Related Indole Alkaloids:  Discovery of Opioid Agonists Structurally Different from Other Opioid Ligands

Hiromitsu Takayama, Hayato Ishikawa, Mika Kurihara et al. · Journal of Medicinal Chemistry · 2002 · 275 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Receptor-mediated inhibition of adenylate cyclase and stimulation of arachidonic acid release in 3T3 fibroblasts. Selective susceptibility to islet-activating protein, pertussis toxin.

Toshihiko Murayama, M Ui · Journal of Biological Chemistry · 1985 · 244 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

Phosphatidic acid may stimulate membrane receptors mediating adenylate cyclase inhibition and phospholipid breakdown in 3T3 fibroblasts.

Toshihiko Murayama, M Ui · Journal of Biological Chemistry · 1987 · 218 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Changes in expressions of proinflammatory cytokines IL-1β, TNF-α and IL-6 in the brain of senescence accelerated mouse (SAM) P8

Kyi Kyi Tha, Yasunobu Okuma, Hiroyuki Miyazaki et al. · Brain Research · 2000 · 162 citations

Life Sciences, Neurobiology, Neuroscience +12