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Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

Oncogenic K-ras PrenylationOncogenic AgentMedicineHuman Tumor GrowthNude Mouse XenograftsCell BiologyTumor SuppressorCancer BiologyRadiation OncologyTumor BiologyCancer Growth