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CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

Michael Zhuo Wang, Janelle Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen,

Drug Metabolism and Disposition · 2006 · 92 citations · 33 references

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33

THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf et al. · Drug Metabolism and Disposition · 2003 · 784 citations

, , +17

Tumor-specific expression of cytochrome P450 CYP1B1.

Graeme I. Murray, M C Taylor, Morag McFadyen et al. · PubMed · 1997 · 534 citations

, , +13

Molecular Cloning and Expression of CYP2J2, a Human Cytochrome P450 Arachidonic Acid Epoxygenase Highly Expressed in Heart

Shu‐Hsing Wu, Cindy R. Moomaw, Kenneth B. Tomer et al. · Journal of Biological Chemistry · 1996 · 481 citations · Full text

, , +14

In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model

J. Brian Houston, Kathryn E. Kenworthy · Drug Metabolism and Disposition · 2000 · 392 citations

, , +17

Cytochrome P450-Derived Arachidonic Acid Metabolism in the Rat Kidney: Characterization of Selective Inhibitors

Mong-Heng Wang, Elimor Brand‐Schieber, Barbara A. Zand et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 232 citations

, , +14