Greg Loewen

Lysosomal Sequestration (Trapping) of Lipophilic Amine (Cationic Amphiphilic) Drugs in Immortalized Human Hepatocytes (Fa2N-4 Cells)

Faraz Kazmi, Tiffini N. Hensley, Chad Pope et al. · Drug Metabolism and Disposition · 2013 · 253 citations · Full text

Medicine, Biochemistry, Pharmacology +15

Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure

Sascha Nicklisch, Steven D. Rees, Aaron P. McGrath et al. · Science Advances · 2016 · 116 citations · Full text

Natural Sciences, Environmental Sciences, Toxicology +5

CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

Michael Zhuo Wang, Janelle Saulter, Etsuko Usuki et al. · Drug Metabolism and Disposition · 2006 · 92 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Membrane Assays to Characterize Interaction of Drugs with ABCB1

Zsolt Fekete, Zsuzsanna Rajnai, Tünde Nagy et al. · The Journal of Membrane Biology · 2015 · 12 citations

Medicine, Molecular Biology, Pharmacology +12