Concepedia

Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

Jing Zhang, Peng Zhan, Jingde Wu, Zhenyu Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu

Bioorganic & Medicinal Chemistry · 2011 · 33 citations · 19 references

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Concepts

References

19

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

Françoise Barré‐Sinoussi, Jean‐Claude Chermann, FA Rey et al. · Science · 1983 · 6.9K citations

, , +16

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

Mikuláš Popovič, M. G. Sarngadharan, Elizabeth J. Read et al. · Science · 1984 · 3.5K citations

, , +17

Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

Christophe Pannecouque, Dirk Daelemans, Erik De Clercq · Nature Protocols · 2008 · 349 citations

, , +14

Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors

Andrew L. Hopkins, Jingshan Ren, Robert Esnouf et al. · Journal of Medicinal Chemistry · 1996 · 343 citations · Full text

, , +16

An improved procedure for the Blaise reaction: a short, practical route to the key intermediates of the saxitoxin synthesis

Steven M. Hannick, Yoshito Kishi · The Journal of Organic Chemistry · 1983 · 177 citations

, , +4