Steven M. Hannick

Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues:  Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

Le Wang, Keith W. Woods, Qun Li et al. · Journal of Medicinal Chemistry · 2002 · 420 citations · Full text

Medicinal Chemistry, Drug Targeting, Oncology +14

An improved procedure for the Blaise reaction: a short, practical route to the key intermediates of the saxitoxin synthesis

Steven M. Hannick, Yoshito Kishi · The Journal of Organic Chemistry · 1983 · 176 citations

Combinatorial Chemistry, Engineering, Altmetric Attention Score +16

Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain:  Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties

Arthur Gomtsyan, Erol K. Bayburt, Robert G. Schmidt et al. · Journal of Medicinal Chemistry · 2005 · 163 citations · Full text

Pain Medicine, Immunology, Receptor Antagonists +18

Stereocontrolled synthesis of C2-symmetric and pseudo-C2-symmetric diamino alcohols and diols for use in HIV protease inhibitors

Dale J. Kempf, Thomas J. Sowin, Elizabeth M. Doherty et al. · The Journal of Organic Chemistry · 1992 · 91 citations

Pharmaceutical Science, Bioorganic Chemistry, Hiv Protease Inhibitors +19

Identification of (<i>R</i>)-1-(5-<i>tert</i>-Butyl-2,3-dihydro-1<i>H</i>-inden-1-yl)-3-(1<i>H</i>-indazol-4-yl)urea (ABT-102) as a Potent TRPV1 Antagonist for Pain Management

Arthur Gomtsyan, Erol K. Bayburt, Robert G. Schmidt et al. · Journal of Medicinal Chemistry · 2008 · 80 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Health Sciences +15