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Novel pyrazole derivatives as neutral CB 1 antagonists with significant activity towards food intake

Ilaria Manca, Andrea Mastinu, Francesca Olimpieri, Matteo Falzoi, Monica Sani, Stefania Ruiu, Giovanni Loriga, Alessandro Volonterio, Simone Tambaro, Mirko Emilio Heiner Bottazzi,

European Journal of Medicinal Chemistry · 2013 · 35 citations · 43 references

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43

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

Murielle Rinaldi‐Carmona, Francis Barth, Michel Héaulme et al. · FEBS Letters · 1994 · 1.8K citations · Full text

, , +14

Leptin-regulated endocannabinoids are involved in maintaining food intake

Vincenzo Di Marzo, Sravan K. Goparaju, Lei Wang et al. · Nature · 2001 · 1.6K citations

, , +12

Effects of Rimonabant on Metabolic Risk Factors in Overweight Patients with Dyslipidemia

Jean‐Pierre Després, Alain Golay, Lars Sjöström · New England Journal of Medicine · 2005 · 1.4K citations · Full text

, , +10

Oxidation of alcohols by “activated” dimethyl sulfoxide. a preparative, steric and mechanistic study

Kanji Omura, Daniel Swern · Tetrahedron · 1978 · 1.2K citations

, , +7