Tricyclic Pyrazoles. 4. Synthesis and Biological Evaluation of Analogues of the Robust and Selective CB₂Cannabinoid Ligand 1-(2‘,4‘-Dichlorophenyl)-6-methyl-<i>N</i>-piperidin-1-yl- 1,4-dihydroindeno[1,2-<i>c</i>]pyrazole-3-carboxamide

Gabriele Murineddu, Paolo Lazzari, Stefania Ruiu, +9

Journal of Medicinal Chemistry

Tricyclic Pyrazoles. Part 1: Synthesis and Biological Evaluation of Novel 1,4-Dihydroindeno[1,2-c]pyrazol-based Ligands for CB1and CB2 Cannabinoid Receptors

Jean‐Mario Mussinu, Stefania Ruiu, Antonio Mulè, +5

Bioorganic & Medicinal Chemistry

Cannabis UseMedicinal ChemistryHeterocyclicBiochemistryFunctional Selectivity +10

Synthesis and Anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties.

Gérard A. Pinna, Giovanni Loriga, Gabriele Murineddu, +5

Chemical and Pharmaceutical Bulletin

ImmunologyDelavirdine AnaloguesChemistryAntiviral DrugPharmaceutical Chemistry +16

Synthesis and application in asymmetric copper(I)-catalyzed allylic oxidation of a new chiral 1,10-phenanthroline derived from pinene

Giorgio Chelucci, Giovanni Loriga, Gabriele Murineddu, +1

Tetrahedron Letters

Chemical EngineeringEngineeringAllylic OxidationOrganic ChemistryAsymmetric Copper +5

Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors

Gabriele Murineddu, Stefania Ruiu, Jean‐Mario Mussinu, +6

Bioorganic & Medicinal Chemistry

Cannabis UseMedicinal ChemistryHeterocyclicFunctional SelectivityMedicine +8

Synthesis and In Vitro Evaluation of the Anti-Viral Activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides

Antonio Carta, Giovanni Loriga, Sandra Piras, +8

Medicinal Chemistry

Crystal StructureMedicinal ChemistryTitle CompoundsPolio VirusMedicine +13

Synthesis and analgesic-antiinflammatory activities of novel acylarylhydrazones with a 5-phenyl-4-R-3-pyrrolyl-acyl moiety

Gabriele Murineddu, Giovanni Loriga, Elisabetta Gavini, +3

Archiv der Pharmazie

Medicinal ChemistryDerivative (Chemistry)Pharmacological StudyArylidene 5-Phenyl-4-r-pyrrole-3-carbohydrazides 1A-jMedicine +13

Tricyclic Pyrazoles. 3. Synthesis, Biological Evaluation, and Molecular Modeling of Analogues of the Cannabinoid Antagonist 8-Chloro-1-(2‘,4‘-dichlorophenyl)-<i>N</i>-piperidin-1-yl-1,4,5,6- tetrahydrobenzo[6,7]cyclohepta[1,2-<i>c</i>]pyrazole-3-carboxamide

Gabriele Murineddu, Stefania Ruiu, Giovanni Loriga, +6

Journal of Medicinal Chemistry

Cannabinoid Antagonist 8-Chloro-1-Chemical ModificationPharmacotherapyHeterocycle ChemistryCannabinoid Pharmacology +17

Novel pyrazole derivatives as neutral CB 1 antagonists with significant activity towards food intake

Ilaria Manca, Andrea Mastinu, Francesca Olimpieri, +10

European Journal of Medicinal Chemistry

Pharmacological StudyBiochemistryNovel Pyrazole DerivativesMedicineFunctional Selectivity +6

Synthesis and Cytotoxic Activities of Pyrrole[2,3-d]pyridazin-4-one Derivatives.

Gabriele Murineddu, Giorgio Cignarella, Giorgio Chelucci, +2

Chemical and Pharmaceutical Bulletin

National Cancer InstituteMedicinal ChemistryCytotoxic ActivitiesRing SystemsPharmaceutical Chemistry +11