Effect of the cyclin-dependent kinases inhibitor p27 on resistance of ovarian cancer multicellular spheroids to anticancer chemotherapy

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

Kornélia Polyák, Jun‐ya Kato, Michael J. Solomon et al. · Genes & Development · 1994 · 2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

Keiko Nakayama, Keiko Nakayama, N. Ishida et al. · Cell · 1996 · 1.6K citations · Full text

Medicine, Endocrinology, Oncology +17

A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

Matthew L. Fero, Michael J. Rivkin, Michael Tasch et al. · Cell · 1996 · 1.5K citations · Full text

Life Sciences, Endocrinology, Genetics +17

Absence of WAF1 mutations in a variety of human malignancies

Masaaki Shiohara, Wafik S. El‐Deiry, M Wada et al. · Blood · 1994 · 371 citations · Full text

Medicine, Molecular Biology, Oncology +10

Impact of the cyclin–dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents

Brad St. Croix, Viví Ann Flørenes, Janusz Rak et al. · Nature Medicine · 1996 · 322 citations

Medicine, Cancer Biology, Oncology +12