Intrathecal administration of beta-endorphin and dynorphin-(1-13) for the treatment of intractable pain

Analgesia Mediated by a Direct Spinal Action of Narcotics

Tony L. Yaksh, Thomas A. Rudy · Science · 1976 · 948 citations

Medicine, Pharmacology, Neuropharmacology +10

Pain Relief by Intrathecally Applied Morphine in Man

Josef K. Wang, Lee A. Nauss, Juergen E. Thomas · Anesthesiology · 1979 · 941 citations · Full text

Medicine, Anesthesiology, Neurology +15

Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness

Floyd E. Bloom, David J. Segal, Nicholas Ling et al. · Science · 1976 · 812 citations

Medicine, Neuroscience, Pharmacology +17

Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

T L Yaksh, Thomas A. Rudy · Journal of Pharmacology and Experimental Therapeutics · 1977 · 554 citations

Medicine, Anesthesiology, Pharmacology +12

Analgesia induced in vivo by central administration of enkephalin in rat

James D. Belluzzi, Norman H. Grant, Victor M. Garsky et al. · Nature · 1976 · 528 citations

Medicine, Pharmacology, Neuropharmacology +11