Concepedia

Intrathecal Administration

Intrathecal Administration is a parenteral route of drug delivery characterized by the injection of therapeutic agents directly into the subarachnoid space of the spinal canal to achieve selective distribution within the cerebrospinal fluid, thereby enabling targeted pharmacological action on the central nervous system.

1.6K

Publications

86K

Citations

6.5K

Authors

1.6K

Institutions

Publications per year

2017–2026

218

Variants

Intrathecal Route

Parents

Publications

1.6K

Targeting Huntingtin Expression in Patients with Huntington’s Disease

New England Journal of Medicine · 2019 · 670 citations · Full text

, , +17

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.

Annika B. Malmberg, T L Yaksh · Journal of Pharmacology and Experimental Therapeutics · 1992 · 653 citations

, , +17

TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

Journal of Clinical Investigation · 2005 · 613 citations · Full text

, , +17

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

Timothy M. Miller, Alan Pestronk, William David et al. · The Lancet Neurology · 2013 · 607 citations · Full text

, , +17

Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord

Dimpy Gupta, Charles H. Tator, Molly S. Shoichet · Biomaterials · 2005 · 587 citations

, , +16

1–5 of 1.6K

Authors

6.5K

  1. TL
    Tony L. Yaksh

    University of California San Diego, United States

    37 publications · 4.3K citations

    30

    h-index

  2. JC
    James C. Eisenach

    Wake Forest University, United States

    20 publications · 1.5K citations

    17

    h-index

  3. SI
    Seiji Ito

    Kansai Medical University, Japan

    15 publications · 1.2K citations

    15

    h-index

  4. RD
    Richard D. Penn

    Rush University Medical Center, United States

    14 publications · 1.4K citations

    14

    h-index

  5. TG
    Torsten Gordh

    Uppsala University Hospital, Sweden

    15 publications · 860 citations

    14

    h-index

1–5 of 6.5K

Institutions

1.6K

  1. University of California San Diego

    San Diego, United States

    28 h-index

    104 publications

    9.1K citations

  2. Stanford University

    Stanford, United States

    22 h-index

    75 publications

    4.4K citations

  3. Wake Forest University

    Winston-Salem, United States

    22 h-index

    72 publications

    4K citations

  4. University of California, San Francisco

    San Francisco, United States

    20 h-index

    126 publications

    5.4K citations

  5. McGill University

    Montreal, Canada

    20 h-index

    59 publications

    3.8K citations

  6. Marymount University

    Arlington, United States

    18 h-index

    36 publications

    1.9K citations

  7. University of Minnesota

    Minneapolis, United States

    17 h-index

    48 publications

    3.6K citations

  8. Osaka Medical and Pharmaceutical University

    Takatsuki, Japan

    17 h-index

    56 publications

    4.3K citations

1–8 of 1.6K

Venues

  1. Pain

    95 publications · 7.3K citations

    52

    h-index

  2. Anesthesiology

    81 publications · 6K citations

    45

    h-index

  3. 44

    h-index

  4. Anesthesia & Analgesia

    116 publications · 4.5K citations

    40

    h-index

  5. British Journal of Pharmacology

    BJP · 42 publications · 2.7K citations

    31

    h-index

1–5