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Structure-based design, synthesis and in vitro characterization of potent 17β-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone

Gabriele Möller, Dominga Deluca, Christian Gege, Andrea Rosinus, Dorota Kowalik, Olaf Peters, Peter Droescher, W. Elger, Jerzy Adamski, Alexander Hillisch

Bioorganic & Medicinal Chemistry Letters · 2009 · 45 citations · 43 references

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References

43

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

Thomas A. Halgren · Journal of Computational Chemistry · 1996 · 5.2K citations

A Fast Flexible Docking Method using an Incremental Construction Algorithm

Matthias Rarey, Bernd Krämer, Thomas Lengauer et al. · Journal of Molecular Biology · 1996 · 2.8K citations

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Synthesis of .alpha.,.beta.-unsaturated carbonyl compounds by palladium(II)-catalyzed dehydrosilylation of silyl enol ethers

Yoshihiko Ito, Toshikazu Hirao, Takeo Saegusa · The Journal of Organic Chemistry · 1978 · 849 citations

, , +12

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative

Bengt Persson, Yvonne Kallberg, James E. Bray et al. · Chemico-Biological Interactions · 2008 · 388 citations · Full text

, , +3

The structure of a complex of human 17β-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors

Rock Breton, Dominique Housset, Catherine Mazza et al. · Structure · 1996 · 209 citations · Full text

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