Concepedia

Hydroxysteroid Dehydrogenases

Hydroxysteroid Dehydrogenase is a steroidogenic enzyme that catalyzes the oxidation or reduction of hydroxyl and keto groups on steroid molecules, thereby regulating the bioactivity and metabolic fate of steroids through position- and stereospecific transformations.

2.6K

Publications

109.4K

Citations

7.4K

Authors

1.5K

Institutions

Publications per year

2017–2026

125

Variants

Hydroxysteroid Dehydrogenase

Parents

Publications

2.6K

11β-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

Yuri Kotelevtsev, Megan C. Holmes, Ann N. Burchell et al. · Proceedings of the National Academy of Sciences · 1997 · 855 citations

, , +17

Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme

Anthony L. Albiston, Varuni Obeyesekere, Zygmunt S. Krozowski · Molecular and Cellular Endocrinology · 1994 · 712 citations

, , +5

Human hypertension caused by mutations in the kidney isozyme of 11β–hydroxysteroid dehydrogenase

Tomoatsu Mune, Fraser M. Rogerson, Heli Nikkilä et al. · Nature Genetics · 1995 · 626 citations

, , +15

Male pseudohermaphroditism caused by mutations of testicular 17β–hydroxysteroid dehydrogenase 3

Wayne M. Geissler, Daphne L. Davis, Ling Wu et al. · Nature Genetics · 1994 · 574 citations

, , +16

Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1‒AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

T.M. Penning, Michael E. Burczynski, Joseph M. Jez et al. · Biochemical Journal · 2000 · 572 citations · Full text

, , +17

1–5 of 2.6K

Authors

7.4K

  1. TP
    T.M. Penning

    University of Pennsylvania, United States

    61 publications · 4.7K citations

    36

    h-index

  2. FL
    Fernand Labrie

    Université Laval, Canada

    53 publications · 4K citations

    32

    h-index

  3. DP
    Donald Poirier

    Université Laval, Canada

    52 publications · 1.9K citations

    28

    h-index

  4. JA
    Jerzy Adamski

    Helmholtz Zentrum München, Germany

    49 publications · 2.2K citations

    27

    h-index

  5. MP
    Matti Poutanen

    University of Turku, Finland

    34 publications · 1.9K citations

    27

    h-index

1–5 of 7.4K

Institutions

1.5K

  1. Université Laval

    Québec, Canada

    46 h-index

    563 publications

    35.3K citations

  2. University of Pennsylvania

    Philadelphia, United States

    40 h-index

    224 publications

    22.7K citations

  3. The University of Texas Southwestern Medical Center

    Dallas, United States

    31 h-index

    145 publications

    15.4K citations

  4. University of Edinburgh

    Edinburgh, United Kingdom

    29 h-index

    151 publications

    18.2K citations

  5. University of Oulu

    Oulu, Finland

    27 h-index

    138 publications

    8.9K citations

  6. Karolinska Institutet

    Stockholm, Sweden

    27 h-index

    125 publications

    6.2K citations

  7. Philipps University of Marburg

    Marburg, Germany

    26 h-index

    97 publications

    3.6K citations

  8. Population Council

    New York, United States

    26 h-index

    89 publications

    4.8K citations

1–8 of 1.5K

Venues

  1. Journal of Biological Chemistry

    JBC · 124 publications · 9.6K citations

    59

    h-index

  2. Endocrinology

    162 publications · 8.4K citations

    53

    h-index

  3. 46

    h-index

  4. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 100 publications · 4.6K citations

    41

    h-index

  5. Molecular and Cellular Endocrinology

    94 publications · 4.2K citations

    37

    h-index

1–5