Wayne M. Geissler

Male pseudohermaphroditism caused by mutations of testicular 17β–hydroxysteroid dehydrogenase 3

Wayne M. Geissler, Daphne L. Davis, Ling Wu et al. · Nature Genetics · 1994 · 572 citations

Spermatogenesis, Male Pseudohermaphroditism, Infertility +8

Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity

Lawrence Wu, Monica Einstein, Wayne M. Geissler et al. · Journal of Biological Chemistry · 1993 · 438 citations · Full text

Genetics, Expression Cloning, Active Steroid Hormones +17

Integrating the Impact of Lipophilicity on Potency and Pharmacokinetic Parameters Enables the Use of Diverse Chemical Space during Small Molecule Drug Optimization

Randy R. Miller, Maria Madeira, Harold B. Wood et al. · Journal of Medicinal Chemistry · 2020 · 119 citations

Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition

B. Azzolina, Kenneth Ellsworth, S Andersson et al. · The Journal of Steroid Biochemistry and Molecular Biology · 1997 · 105 citations

Molecular Pharmacology, Aldo-keto Reductase, Biochemistry +7

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1

J. Rotonda, Margarita García‐Calvo, Herb G. Bull et al. · Chemistry & Biology · 2001 · 84 citations · Full text

Mitophagy, Cleavage Specificity, Biochemistry +13