Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +16

Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Lori D. Klaman, Olivier Boss, Odile D. Peroni et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

Life Sciences, Endocrinology, Molecular Biology +17

Genome Scan for Human Obesity and Linkage to Markers in 20q13

Joseph H. Lee, Danielle R. Reed, Weidong Li et al. · The American Journal of Human Genetics · 1999 · 239 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Osmotic Loading of Neutralizing Antibodies Demonstrates a Role for Protein-tyrosine Phosphatase 1B in Negative Regulation of the Insulin Action Pathway

Faiyaz Ahmad, Pei-Ming Li, Joseph Meyerovitch et al. · Journal of Biological Chemistry · 1995 · 231 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

A Variation in 3′ UTR of hPTP1B Increases Specific Gene Expression and Associates with Insulin Resistance

Rosa Di Paola, Lucia Frittitta, Giuseppe Miscio et al. · The American Journal of Human Genetics · 2002 · 188 citations · Full text

Life Sciences, Genetics, Molecular Biology +9